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. 1972 Jan;5(1):127–131. doi: 10.1128/iai.5.1.127-131.1972

Mycoplasmacidal Activity of Peroxidase-H2O2-Halide Systems 1

A A Jacobs a, I E Low a, B B Paul a, R R Strauss a, A J Sbarra a
PMCID: PMC422332  PMID: 4656352

Abstract

A mycoplasmacidal system consisting of myeloperoxidase (MPO)-containing granules, H2O2, and a halide is described. In all parameters measured, it appears to be identical to the MPO-H2O2-halide bactericidal system previously reported. It has a pH optimum of approximately 5.5 and an optimal MPO:H2O2 ratio of 1:25. The halide requirement can be satisfied by either chloride or iodide. Through the use of taurine or horseradish peroxidase substitution, chloride-mediated killing can be distinguished from iodide-mediated killing. The relationship of this mycoplasmacidal system to other mycoplasmacidal systems and to host surveillance of mycoplasma is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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