Abstract
A screening test for chronic granulomatous disease is described; it is based on abnormal oxidation of glucose-1-14C to 14CO2 during phagocytosis by leukocytes in whole blood.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baehner R. L., Nathan D. G. Quantitative nitroblue tetrazolium test in chronic granulomatous disease. N Engl J Med. 1968 May 2;278(18):971–976. doi: 10.1056/NEJM196805022781801. [DOI] [PubMed] [Google Scholar]
- Douglas S. D. Analytic review: disorders of phagocyte function. Blood. 1970 Jun;35(6):851–866. [PubMed] [Google Scholar]
- Douglas S. D., Davis W. C., Fudenberg H. H. Granulocytopathies: pleomorphism of neutrophil dysfunction. Am J Med. 1969 Jun;46(6):901–909. doi: 10.1016/0002-9343(69)90091-6. [DOI] [PubMed] [Google Scholar]
- Douglas S. D., Spicer S. S. Acid phosphatase cytochemistry of phagocytizing leukocytes from patients with chronic granulomatous disease. Infect Immun. 1971 Jan;3(1):179–183. doi: 10.1128/iai.3.1.179-183.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gifford R. H., Malawista S. E. A simple rapid micromethod for detecting chronic granulomatous disease of childhood. J Lab Clin Med. 1970 Mar;75(3):511–519. [PubMed] [Google Scholar]
- Good R. A., Quie P. G., Windhorst D. B., Page A. R., Rodey G. E., White J., Wolfson J. J., Holmes B. H. Fatal (chronic) granulomatous disease of childhood: a hereditary defect of leukocyte function. Semin Hematol. 1968 Jul;5(3):215–254. [PubMed] [Google Scholar]
- Holmes B., Page A. R., Good R. A. Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function. J Clin Invest. 1967 Sep;46(9):1422–1432. doi: 10.1172/JCI105634. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Keusch G. T., Weinstein L., Grady G. F. Biochemical effects of cholera enterotoxin. II. Glucose metabolism in the intestine of the infant rabbit. J Infect Dis. 1971 Aug;124(2):188–193. doi: 10.1093/infdis/124.2.188. [DOI] [PubMed] [Google Scholar]
- Kvarstein B., Halvorsen K. S. Oxygen consumption during the initial stage of human leucocyte phagocytosis as a test for chronic granulomatous disease. Scand J Clin Lab Invest. 1970 Sep;26(2):175–178. doi: 10.3109/00365517009049231. [DOI] [PubMed] [Google Scholar]
- Skeel R. T., Yankee R. A., Henderson E. S. Hexose monophosphate shunt activity of circulating phagocytes in acute lymphocytic leukemia. J Lab Clin Med. 1971 Jun;77(6):975–984. [PubMed] [Google Scholar]
- Skeel R. T., Yankee R. A., Spivak W. A., Novikovs L., Henderson E. S. Leukocyte preservation. I. Phagocytic stimulation of the hexose monophosphate shunt as a measure of cell viability. J Lab Clin Med. 1969 Feb;73(2):327–337. [PubMed] [Google Scholar]