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. 1972 Apr;5(4):524–530. doi: 10.1128/iai.5.4.524-530.1972

Agglutination of Staphylococcus aureus by Rabbit Sera

Arne Forsgren 1, Urban Forsum 1
PMCID: PMC422401  PMID: 4564678

Abstract

Of 137 Staphylococcus aureus strains, 87 agglutinated in normal rabbit serum. The agglutination was shown to be caused by the Fc-part of immunoglobulin G (IgG). F(ab1)2-fragments of IgG and immunoglobulin M (IgM) in corresponding concentrations were unreactive. The agglutinating strains had a high or moderate content of protein A. Strains with a low content of protein A and protein A-negative mutants did not agglutinate. The importance of the reaction between the Fc part of IgG and protein A for serotyping of S. aureus is demonstrated. Two alternative methods for serotyping S. aureus are suggested, using either F(ab1)2 fragments of IgG or intact IgM.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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