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. 1972 Jun;5(6):921–926. doi: 10.1128/iai.5.6.921-926.1972

Infection of Genital Tract and Transmission of Ocular Infection to Newborns by the Agent of Guinea Pig Inclusion Conjunctivitis

David T Mount 1, Pierluigi E Bigazzi 1, Almen L Barron 1
PMCID: PMC422464  PMID: 4344096

Abstract

Female guinea pigs were inoculated intravaginally with the agent of guinea pig inclusion conjunctivitis (Gp-ic). Evidence for infection was obtained by demonstration of Gp-ic inclusions in epithelial cells of genital tract smears, histopathology, recovery of Gp-ic during infection, and antibody response. Infection of the genital tract was produced with low doses (20-200 median egg lethal doses) of the agent. The infection lasted about 3 weeks, and there was no marked clinical response. Ocular infection that could be detected as early as 3 days after birth in offspring of infected mothers was also demonstrated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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