Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1972 Jun;5(6):987–989. doi: 10.1128/iai.5.6.987-989.1972

Effect of Vitamin E on the Immune Response of Hypoxic and Normal Chickens

Robert P Tengerdy 1, Rollin H Heinzerling 1, Cheryl F Nockels 1
PMCID: PMC422477  PMID: 4564409

Abstract

Chicks and hens raised on a diet enriched with 60 mg of vitamin E per lb. of feed had a significantly increased immune response as measured by the antibody plaque-forming cell test or by hemagglutination. Since the effect was much greater on hypoxic (simulated altitude exposed) chicks, a synergistic effect between hypoxia and vitamin E may be suggested.

Full text

PDF
987

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alm G. V. The in vivo spleen response to sheep erythrocytes in bursectomized-irradiated chickens. Acta Pathol Microbiol Scand B Microbiol Immunol. 1970;78(5):641–646. doi: 10.1111/j.1699-0463.1970.tb04350.x. [DOI] [PubMed] [Google Scholar]
  2. Cunningham A. J., Szenberg A. Further improvements in the plaque technique for detecting single antibody-forming cells. Immunology. 1968 Apr;14(4):599–600. [PMC free article] [PubMed] [Google Scholar]
  3. Fitch C. D. Experimental anemia in primates due to vitamin E deficiency. Vitam Horm. 1968;26:501–514. doi: 10.1016/s0083-6729(08)60768-2. [DOI] [PubMed] [Google Scholar]
  4. JERNE N. K., NORDIN A. A. Plaque formation in agar by single antibody-producing cells. Science. 1963 Apr 26;140(3565):405–405. [PubMed] [Google Scholar]
  5. KRISHNAMURTHY S., BIERI J. G. THE ABSORPTION, STORAGE, AND METABOLISM OF ALPHA-TOCOPHEROL-C14 IN THE RAT AND CHICKEN. J Lipid Res. 1963 Jul;4:330–336. [PubMed] [Google Scholar]
  6. Mellors A., Tappel A. L. The inhibition of mitochondrial peroxidation by ubiquinone and ubiquinol. J Biol Chem. 1966 Oct 10;241(19):4353–4356. [PubMed] [Google Scholar]
  7. Silber R., Winter R., Kayden H. J. Tocopherol transport in the rat erythrocyte. J Clin Invest. 1969 Nov;48(11):2089–2095. doi: 10.1172/JCI106175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sterzl J., Ríha I. Detection of cells producing 7S antibodies by the plaque technique. Nature. 1965 Nov 27;208(5013):858–859. doi: 10.1038/208858a0. [DOI] [PubMed] [Google Scholar]
  9. Tengerdy R. P., Kramer T. Immune response of rabbits during short term exposure to high altitude. Nature. 1968 Jan 27;217(5126):367–369. doi: 10.1038/217367a0. [DOI] [PubMed] [Google Scholar]
  10. Wu A. M., Till J. E., Siminovitch L., McCulloch E. A. Cytological evidence for a relationship between normal hemotopoietic colony-forming cells and cells of the lymphoid system. J Exp Med. 1968 Mar 1;127(3):455–464. doi: 10.1084/jem.127.3.455. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES