Abstract
Addition of 100 μg of polyadenylic: polyuridylic (poly A:U) complex to each dose of inactivated rabies vaccine increased immunity to rabies challenge in mice. Stimulation was also observed after addition of 10 μg of poly A:U to the vaccines. Mixtures of rabies vaccine and poly A:U lost their stimulatory properties after storage at 37 or 4 C for 1 month. However, these data are encouraging for practical use of poly A:U as an adjuvant to viral vaccines.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Branche R., Lang R., Petermann H. G., Soulebot J. P. Vaccin rabique inactivé produit à partir de culture cellulaire. Résultats PR'ELIMINAIRES. Prog Immunobiol Stand. 1967;3:144–150. [PubMed] [Google Scholar]