Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1973 Feb;7(2):205–211. doi: 10.1128/iai.7.2.205-211.1973

Antigens of Streptococcus sanguis

Burton Rosan 1
PMCID: PMC422661  PMID: 4633291

Abstract

An antigenic analysis of the alpha-hemolytic streptococci isolated from dental plaque was performed by use of antisera against a strain of Streptococcus sanguis (M-5) which was isolated from dental plaque. Immunoelectrophoretic and Ouchterlony tests of Rantz and Randall extracts of 45 strains gave positive reactions with the M-5 antisera. These strains represented 60% of the strains tested. The number of antigens which could be identified in these extracts varied from one to five and were designated a to e. The a antigen was found in 36 of the strains tested, including reference strains of S. sanguis and the group H streptococci. The strains reacting with the M-5 antisera were divided into two majors types: type I consisted of 23 strains in which the a antigen was found alone or with one or more of the c, d, and e antigens; type II consisted of 13 strains in which both the a and b antigens were found with or without one or more of the c, d, and e antigens. The remaining strains contained, either singly or in combination, the b, c, d, and e antigens but not the a antigen. Biochemical tests of representatives of each serotype and reference strains indicated that strains reacting with M-5 antisera were S. sanguis. These findings suggest that S. sanguis strains share common physiological and serological properties.

Full text

PDF
205

Images in this article

207Image
on p.207
207Image
on p.207
208Image
on p.208
208Image
on p.208
208Image
on p.208
209Image
on p.209
209Image
on p.209
209Image
on p.209

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARMSTRONG J. J., BADDILEY J., BUCHANAN J. G. Structure of the ribitol teichoic acid from the walls of Bacillus subtilis. Biochem J. 1960 Sep;76:610–621. doi: 10.1042/bj0760610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Archibald A. R., Baddiley J. The teichoic acids. Adv Carbohydr Chem Biochem. 1966;21:323–375. doi: 10.1016/s0096-5332(08)60320-3. [DOI] [PubMed] [Google Scholar]
  3. BARBER C., CORALIA-BALDOVIN-AGAPI, BELOIU I., PLECEAS P. [Contribution to the study of the antigenic structure of non-hemolytic streptococci. III. The antigens of the group "D" streptococci (enterococci)]. Arch Roum Pathol Exp Microbiol. 1962 Mar;21:115–129. [PubMed] [Google Scholar]
  4. BLEIWEIS A. S., KRAUSE R. M. THE CELL WALLS OF GROUP D STREPTOCOCCI. I. THE IMMUNOCHEMISTRY OF THE TYPE 1 CARBOHYDRATE. J Exp Med. 1965 Aug 1;122:237–249. doi: 10.1084/jem.122.2.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bleiweis A. S., Craig R. A., Zinner D. D., Jablon J. M. Chemical composition of purified cell walls of cariogenic streptococci. Infect Immun. 1971 Jan;3(1):189–191. doi: 10.1128/iai.3.1.189-191.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bratthall D. Demonstration of five serological groups of streptococcal strains resembling Streptococcus mutans. Odontol Revy. 1970;21(2):143–152. [PubMed] [Google Scholar]
  7. Carlsson J. A numerical taxonomic study of human oral streptococci. Odontol Revy. 1968;19(2):137–160. [PubMed] [Google Scholar]
  8. FARMER E. D. Serological subdivisions among the Lancefield group H streptococci. J Gen Microbiol. 1954 Oct;11(2):131–138. doi: 10.1099/00221287-11-2-131. [DOI] [PubMed] [Google Scholar]
  9. KRAUSE R. M., MCCARTY M. Studies on the chemical structure of the streptococcal cell wall. I. The identification of a mucopeptide in the cell walls of groups A and A-variant streptococci. J Exp Med. 1961 Jul 1;114:127–140. doi: 10.1084/jem.114.1.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kalonaros I. V., Bahn A. N. Antigenic composition of the cell wall of Streptococcus mitis. Arch Oral Biol. 1965 Jul-Aug;10(4):625–633. doi: 10.1016/0003-9969(65)90008-7. [DOI] [PubMed] [Google Scholar]
  11. Matsuno T., Slade H. D. Composition and properties of a group A streptococcal teichoic acid. J Bacteriol. 1970 Jun;102(3):747–752. doi: 10.1128/jb.102.3.747-752.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Maxted W. R., Fraser C. A. Sensitivity to acid of the type antigens of Streptococcus faecalis. J Gen Microbiol. 1966 Apr;43(1):145–150. doi: 10.1099/00221287-43-1-145. [DOI] [PubMed] [Google Scholar]
  13. OTTENS H., WINKLER K. C. Indifferent and haemolytic streptococci possessing group-antigen F. J Gen Microbiol. 1962 Apr;28:181–191. doi: 10.1099/00221287-28-1-181. [DOI] [PubMed] [Google Scholar]
  14. RANTZ L. A., RANDALL E. Use of autoclaved extracts of hemolytic streptococci for serological grouping. Stanford Med Bull. 1955 May;13(2):290–291. [PubMed] [Google Scholar]
  15. Ranhand J. M., Leonard C. G., Cole R. M. Autolytic activity associated with competent group H streptococci. J Bacteriol. 1971 Apr;106(1):257–268. doi: 10.1128/jb.106.1.257-268.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Sherman J. M., Niven C. F., Smiley K. L. Streptococcus salivarius and Other Non-hemolytic Streptococci of the Human Throat. J Bacteriol. 1943 Mar;45(3):249–263. doi: 10.1128/jb.45.3.249-263.1943. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. WICKEN A. J., ELLIOTT S. D., BADDILEY J. The identity of streptococcal group D antigen with teichoic acid. J Gen Microbiol. 1963 May;31:231–239. doi: 10.1099/00221287-31-2-231. [DOI] [PubMed] [Google Scholar]
  18. Washburn M. R., White J. C., Niven C. F., Jr Streptococcus S.B.E.: Immunological Characteristics. J Bacteriol. 1946 Jun;51(6):723–729. doi: 10.1128/jb.51.6.723-729.1946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. White J. C., Niven C. F., Jr Streptococcus S.B.E.: A Streptococcus Associated with Subacute Bacterial Endocarditis. J Bacteriol. 1946 Jun;51(6):717–722. doi: 10.1128/jb.51.6.717-722.1946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Wicken A. J., Knox K. W. Studies on the group F antigen of lactobacilli: isolation of a teichoic acid-lipid complex from Lactobacillus fermenti NCTC 6991. J Gen Microbiol. 1970 Mar;60(3):293–301. doi: 10.1099/00221287-60-3-293. [DOI] [PubMed] [Google Scholar]
  21. ZINNER D. D., JABLON J. M., HADDOX C. H., Jr, ARAN A., SASLAW M. S. USE OF FLUORESCENT-ANTIBODY TECHNIQUE TO IDENTIFY EXPERIMENTAL HAMSTER AND RAT STRAINS OF CARIOGENIC STREPTOCOCCI. J Dent Res. 1965 May-Jun;44:471–475. doi: 10.1177/00220345650440030501. [DOI] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES