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. 1973 Mar;7(3):329–334. doi: 10.1128/iai.7.3.329-334.1973

Role of Delayed Hypersensitivity in Blastomycosis of Mice

Harry D Spencer a,1, George C Cozad a
PMCID: PMC422679  PMID: 4713689

Abstract

C57BL/6J mice rendered hypersensitive to Blastomyces dermatitidis were protected from the lethal effects of a blastomyces infection. This protection was observed following a lethal intraperitoneal challenge with viable cells 15 days after subcutaneous inoculation with 3.9 × 104 viable cells. Delayed hypersensitivity was induced in C57 mice by two injections of Merthiolate-killed cells in adjuvant or by a single injection of viable cells. Development of hypersensitivity was determined at appropriate intervals by footpad injection with killed yeast cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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