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. 1973 May;7(5):771–776. doi: 10.1128/iai.7.5.771-776.1973

Enhanced Effect of Repeated Administration of Bacterial Vaccine Against Viral Respiratory Infection

Miklos Degré 1, Helen Dahl 1
PMCID: PMC422759  PMID: 4357990

Abstract

Administration of a standard bacterial vaccine (SBV) affords some protection against influenza infection in mice if given 4 to 5 h before inoculation of the virus. This effect was enhanced by repeated injections of SBV 7 and 14 days earlier, as measured by the length of survival, mortality rate, development of gross pneumonia, and virus multiplication in the lungs. Serum interferon levels were likewise enhanced by immunization with SBV, which may, at least in part, explain the increased preventive effect.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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