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. 1973 Aug;8(2):272–277. doi: 10.1128/iai.8.2.272-277.1973

Hypogammaglobulinemia and Thymic Hypoplasia in Horses: a Primary Combined Immunodeficiency Disorder

T C McGuire 1, Marinel J Poppie 1
PMCID: PMC422843  PMID: 4199158

Abstract

A severe combined immunodeficiency disorder was demonstrated in two Arabian foals which were full siblings. The defect in the B-lymphocyte system was shown by hypogammaglobulinemia, lymphopenia, and absence of germinal centers. The almost total absence of thymic tissue in one foal and the lack of thymic dependent lymphocytes in the spleens of both foals demonstrate a T-lymphocyte defect. In a retrospective study of total available Arabian foal cases, 4 of 15 had evidence of immunodeficiency.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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