Abstract
Cell-bound and cell-free herpesvirus of turkeys infected and replicated in guinea pig cell cultures as evidenced by cytopathic effects, intranuclear inclusions, and the presence of herpesvirus particles as seen by electron microscopy were studied in this investigation. Further evidence for the replication of herpesvirus of turkeys in cell cultures was determined by serum neutralization, complement fixation, and the fluorescent antibody tests.
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- Bedigian H. G., Sevoian M. Susceptibility of mammalian (hamster) cell culture to infection with herpesvirus of turkeys. Appl Microbiol. 1972 Aug;24(2):275–280. doi: 10.1128/am.24.2.275-280.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hamdy F., Sevoian M. Complement fixation reaction for the diagnosis of type II avian (Marek's) leukosis. Appl Microbiol. 1970 Sep;20(3):356–361. doi: 10.1128/am.20.3.356-361.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kawamura H., King D. J., Jr, Anderson D. P. A herpesvirus isolated from kidney cell culture of normal turkeys. Avian Dis. 1969 Nov;13(4):853–863. [PubMed] [Google Scholar]
- MADIN S. H., ANDRIESE P. C., DARBY N. B. The in vitro cultivation of tissues of domestic and laboratory animals. Am J Vet Res. 1957 Oct;18(69):932–941. [PubMed] [Google Scholar]
- Okazaki W., Purchase H. G., Burmester B. R. Protection against Marek's disease by vaccination with a herpesvirus of turkeys. Avian Dis. 1970 May;14(2):413–429. [PubMed] [Google Scholar]
- Purchase H. G., Burmester B. R., Cunningham C. H. Responses of cell cultures from various avian species to Marek's disease virus and herpesvirus of turkeys. Am J Vet Res. 1971 Nov;32(11):1811–1823. [PubMed] [Google Scholar]
- ROIZMAN B. Polykaryocytosis induced by viruses. Proc Natl Acad Sci U S A. 1962 Feb;48:228–234. doi: 10.1073/pnas.48.2.228. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Spencer J. L., Calnek B. W. Marek's disease: application of immunofluorescence for detection of antigen and antibody. Am J Vet Res. 1970 Feb;31(2):345–358. [PubMed] [Google Scholar]
- WELLER T. H., WITTON H. M., BELL E. J. The etiologic agents of varicella and herpes zoster; isolation, propagation, and cultural characteristics in vitro. J Exp Med. 1958 Dec 1;108(6):843–868. doi: 10.1084/jem.108.6.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Witter R. L., Nazerian K., Purchase H. G., Burgoyne G. H. Isolation from turkeys of a cell-associated herpesvirus antigenically related to Marek's disease virus. Am J Vet Res. 1970 Mar;31(3):525–538. [PubMed] [Google Scholar]