Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1973 Sep;8(3):488–490. doi: 10.1128/iai.8.3.488-490.1973

Separation of Serum Bactericidal and Opsonizing Activities for Haemophilus influenzae Type b

Simon L Newman 1, Bryson Waldo 1, Richard B Johnston Jr 1
PMCID: PMC422876  PMID: 4542337

Abstract

When assay conditions permitted bacterial growth, immune serum had no bactericidal activity for Haemophilus influenzae but promoted rapid phagocytic killing of this organism by human leukocytes.

Full text

PDF
488

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson P., Johnston R. B., Jr, Smith D. H. Human serum activities against Hemophilus influenzae, type b. J Clin Invest. 1972 Jan;51(1):31–38. doi: 10.1172/JCI106793. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Anderson P., Peter G., Johnston R. B., Jr, Wetterlow L. H., Smith D. H. Immunization of humans with polyribophosphate, the capsular antigen of Hemophilus influenzae, type b. J Clin Invest. 1972 Jan;51(1):39–44. doi: 10.1172/JCI106794. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Baehner R. L., Johnston R. B., Jr Metabolic and bactericidal activities of human eosinophils. Br J Haematol. 1971 Mar;20(3):277–285. doi: 10.1111/j.1365-2141.1971.tb07038.x. [DOI] [PubMed] [Google Scholar]
  4. Johnston R. B., Jr, Anderson P., Rosen F. S., Smith D. H. Characterization of human antibody to polyribophosphate, the capsular antigen of Hemophilus influenzae, type B. Clin Immunol Immunopathol. 1973 Jan;1(2):234–240. doi: 10.1016/0090-1229(73)90024-x. [DOI] [PubMed] [Google Scholar]
  5. Johnston R. B., Jr, Baehner R. L. Chronic granulomatous disease: correlation between pathogenesis and clinical findings. Pediatrics. 1971 Nov;48(5):730–739. [PubMed] [Google Scholar]
  6. Johnston R. B., Jr, Klemperer M. R., Alper C. A., Rosen F. S. The enhancement of bacterial phagocytosis by serum. The role of complement components and two cofactors. J Exp Med. 1969 Jun 1;129(6):1275–1290. doi: 10.1084/jem.129.6.1275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kaplan E. L., Laxdal T., Quie P. G. Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci. Pediatrics. 1968 Mar;41(3):591–599. [PubMed] [Google Scholar]
  8. Quie P. G., White J. G., Holmes B., Good R. A. In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest. 1967 Apr;46(4):668–679. doi: 10.1172/JCI105568. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES