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. 1973 Nov;8(5):814–818. doi: 10.1128/iai.8.5.814-818.1973

Polyarthritis Associated with Salmonella Infection in Rats

Alvin Volkman 1, Frank M Collins 1
PMCID: PMC422932  PMID: 4584053

Abstract

Rats infected intravenously with Salmonella enteritidis develop a chronic destructive polyarthritis. The joint lesions resemble those of human rheumatoid arthritis in distribution and pathology. On the basis of histological and microbiological studies, involvement does not appear to be the result of intra-articular sepsis. Instead, the data favor the view that transient infection incites an immunological response that localizes in the joint and becomes destructive.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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