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CXCL1 blockade prevents mouse intracranial aneurysm formation
A) Experimental scheme. B) Representative pictures of Circle of Willis from IgG- and anti-CXCL1-treated mice (scalebar=2 mm). C) Mice treated with CXCL1-neutralizing antibody over two weeks develop significantly less aneurysms than IgG2A treated mice (p=0.0078). Data are presented as mean±s.e.m.
