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. 1974 Dec;10(6):1443–1444. doi: 10.1128/iai.10.6.1443-1444.1974

Inability to Detect Hepatitis B Virus or Specific Antigens in Transformed Chimpanzee Lymphocytes

C A Schable 1, B L Murphy 1, K R Berquist 1, C R Gravelle 1, J E Maynard 1
PMCID: PMC423124  PMID: 4373398

Abstract

Transformed chimpanzee lymphocytes were examined to determine whether they would support the replication of hepatitis B virus. After 5 months, no hepatitis B virus, hepatitis B surface antigen, or antibody to hepatitis B surface antigen was detected.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agarwal S. S., Blumberg B. S., Gerstley B. J., London W. T., Sutnick A. I., Loeb L. A. DNA polymerase activity as an index of lymphocyte stimulation: studies in Down's syndrome. J Clin Invest. 1970 Jan;49(1):161–169. doi: 10.1172/JCI106215. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Barker L. F., Chisari F. V., McGrath P. P., Dalgard D. W., Kirschstein R. L., Almeida J. D., Edington T. S., Sharp D. G., Peterson M. R. Transmission of type B viral hepatitis to chimpanzees. J Infect Dis. 1973 Jun;127(6):648–662. doi: 10.1093/infdis/127.6.648. [DOI] [PubMed] [Google Scholar]
  3. Dreesman G. R., Hollinger F. B., Suriano J. R., Fujioka R. S., Brunschwig J. P., Melnick J. L. Biophysical and biochemical heterogeneity of purified hepatitis B antigen. J Virol. 1972 Sep;10(3):469–476. doi: 10.1128/jvi.10.3.469-476.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hersey D. F., Shaw E. D. Viral agents in hepatitis. A review. Lab Invest. 1968 Nov;19(5):558–572. [PubMed] [Google Scholar]
  5. Hirschman S. Z., Schwartz J., Vernace S., Schaffner F., Ganz C. An electron microscopic study of the structural polymorphism of hepatitis B antigen. J Infect Dis. 1973 Nov;128(5):605–617. doi: 10.1093/infdis/128.5.605. [DOI] [PubMed] [Google Scholar]
  6. Hoofnagle J. H., Gerety R. J., Barker L. F. Antibody to hepatitis-B-virus core in man. Lancet. 1973 Oct 20;2(7834):869–873. doi: 10.1016/s0140-6736(73)92004-7. [DOI] [PubMed] [Google Scholar]
  7. Krugman S., Giles J. P., Hammond J. Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection. JAMA. 1967 May 1;200(5):365–373. doi: 10.1001/jama.200.5.365. [DOI] [PubMed] [Google Scholar]
  8. Laiwah A. A. Lymphocyte transformation by Australia antigen. Lancet. 1971 Aug 28;2(7722):470–471. doi: 10.1016/s0140-6736(71)92633-x. [DOI] [PubMed] [Google Scholar]
  9. Maynard J. E., Hartwell W. V., Berquist K. R. Hepatitis-associated antigen in chimpanzees. J Infect Dis. 1971 Jun;123(6):660–664. doi: 10.1093/infdis/123.6.660. [DOI] [PubMed] [Google Scholar]
  10. Miller G., Lipman M. Comparison of the yield of infectious virus from clones of human and simian lymphoblastoid lines transformed by Epstein-Barr virus. J Exp Med. 1973 Dec 1;138(6):1398–1412. doi: 10.1084/jem.138.6.1398. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Petri I. B., Mészáros E. J. Letter: Persistence of Au-SH antigen and lymphocyte transformation. Lancet. 1973 Oct 6;2(7832):802–803. doi: 10.1016/s0140-6736(73)91080-5. [DOI] [PubMed] [Google Scholar]
  12. Sutnick A. I., Bugbee S. J., London W. T., Loeb L. A., Peyretti F., Litwin S., Blumberg B. S. Lymphocyte function in normal people with persistent Australia antigen. J Lab Clin Med. 1973 Jul;82(1):79–85. [PubMed] [Google Scholar]
  13. Truitt R. L., Schechmeister I. L. The replication of bovine viral diarrhea-mucosal disease virus in bovine leukocytes in vitro. Arch Gesamte Virusforsch. 1973;42(1):78–87. doi: 10.1007/BF01250509. [DOI] [PubMed] [Google Scholar]
  14. WARD R., KRUGMAN S., GILES J. P., JACOBS A. M., BODANSKY O. Infectious hepatitis; studies of its natural history and prevention. N Engl J Med. 1958 Feb 27;258(9):407–416. doi: 10.1056/NEJM195802272580901. [DOI] [PubMed] [Google Scholar]

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