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. 1985 Feb;75(2):667–671. doi: 10.1172/JCI111745

Presence of lipid hydroperoxide in human plasma.

M A Warso, W E Lands
PMCID: PMC423552  PMID: 3919062

Abstract

Using purified prostaglandin (PG) H synthase, which synthesizes PGG2 and PGH2 from arachidonic acid, we were able to assay for the presence of peroxide activators in biological tissues. This assay system, capable of detecting both hydrogen peroxide (H2O2) and lipid hydroperoxides, detected a significant amount of synthase activator in plasma. Treatment of the active preparations with catalase and glutathione peroxidase showed that the principal activator in normal human plasma was a lipid hydroperoxide rather than H2O2.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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