Abstract
Background Information:
Limited research has suggested that rural residents are at increased risk of dementia.
Objective:
The objective of this study is to determine if rural residence is associated with dementia using both cross-sectional and prospective analyses.
Methods:
In 1991, 1763 community-dwelling adults aged 65+ participated in the Manitoba Study of Health and Aging (MSHA), which sampled all regions of the province of Manitoba. Baseline measures included age, gender, years of education, the Modified Mini-Mental State Examination (3MS), and rural/urban status. Rural was defined as a census subdivision with a population <20,000 and urban as 20,000+. Dementia was diagnosed in participants with a 3MS score <78 and clinical examination applying DSMIIIR criteria at baseline and at follow-up five years later. All other participants were categorized as not demented. Two analyses were conducted: 1) a cross-sectional analysis (N=1,763), and 2) a prospective analysis of those who did not have dementia at time 1, and who survived to time 2 (N=1,079).
Results:
Forty per cent (n=703) of participants were rural residents. Participants in urban areas had a mean 3MS score of 86.1 vs. 84.2 in rural areas (p = .001). Mean number of years of education in urban areas was 10.0 vs. 8.3 in rural areas (p <.001). In multivariate logistic regression models adjusting for age, gender, and education, living in a rural area was not significantly associated with dementia in either cross-sectional (adjusted Odds Ratio (AOR)=1.03, 95% CI=0.59–1.81) or prospective analyses (AOR=0.78; 95% CI=0.51–1.21).
Conclusion:
Rural residents had significantly lower educational attainment and 3MS scores than urban residents. However, rural residence was not associated with dementia in either cross-sectional or prospective analyses. Further study into heterogeneity between rural areas is warranted.
