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. 2014 Nov 24;6(11):4683–4702. doi: 10.3390/v6114683

Table 1.

Viral proteins that bind CUL4-DDB1.

Virus family Virus (protein) 1 Cellular pathway altered Reference
Paramyxoviridae Simian Virus 5 (V) Innate immunity [97]
HPIV2 (V) Innate immunity [96]
Mumps (V) Innate immunity [104]
Hepadnaviridae HBV (HBx) Unknown -
Retroviridae HIV-1 (Vpr) Cell cycle [105,106]
HIV-2 (Vpx) Cell cycle [107]
Flaviviridae HCV (NS3/4A) Unknown -
Herpesviridae MHV-68 (M2) Apoptosis [108]
EBV (BPLF1) Cell cycle [88]
BHV-1 (VP8) Unknown -

1 HPIV2, Human Parainfluenza Virus 2; HIV-1, Human Immunodeficiency Virus type I; MHV 68, Murine Gammaherpesvirus; EBV, Epstein Barr Virus; HIV-2, Human Immunodeficiency Virus Type II; HCV, hepatitis C virus; BHV-1, Bovine Herpesvirus 1.