TABLE 3 ] .
Baseline Characteristics of Participants by > 10% Emphysema
| Characteristic | > 10% Emphysema (n = 53) | ≤ 10% Emphysema (n = 150) | P Value |
| Age, y | 57 (52-61) | 52 (47-57) | < .001 |
| Male sex | 96 | 91 | .2 |
| Race/ethnicity | .3 | ||
| Black | 70 | 68 | |
| White | 25 | 19 | |
| Hispanic/other | 6 | 13 | |
| BMI, kg/m2 | 24.2 (21.2-27.8) | 28.1 (25.2-32.3) | < .001 |
| Cigarette smoking history | .001 | ||
| Never smoker | 2 | 23 | |
| Former smoker | 22 | 23 | |
| Pack-y | 41 (15-50) | 17 (3-33) | .07 |
| Current smoker | 76 | 54 | |
| Pack-y | 36 (18-48) | 21 (10 -34) | .002 |
| Other substance abuse, ever | |||
| Marijuana (smoked) | 92 | 75 | .007 |
| Alcohol | 22 | 23 | .8 |
| Injection drug use | 24 | 22 | .7 |
| COPD (FEV1/FVC < LLN) | 36 | 9 | < .001 |
| Dlco, % predicted | 56.9 (47.4-64.2) | 68.4 (58.6-78.3) | < .001 |
| FEV1, % predicted | 88.4 (75.6-98.3) | 92.1 (82-104.7) | .06 |
| Prior pneumonia | |||
| Bacterial, community acquired | 22 | 9 | .02 |
| Pneumocystis jirovecii | 0 | 1 | 1.0 |
| Mycobacterium tuberculosis | 9 | 3 | .1 |
| HIV infection | 72 | 51 | .008 |
| HIV-related variables (n = 114)a | |||
| CD4 count, cells/μL | 384 (304-591) | 447 (323-633) | .3 |
| CD4 < 200 cells/μL | 21 | 11 | .2 |
| Nadir CD4 < 200 cells/μL | 74 | 54 | .04 |
| Detectable HIV RNA (≥ 400 copies/mL) | 24 | 18 | .6 |
| ART use | 92 | 93 | 1.0 |
Data are presented as median (interquartile range) or %. See Table 1 legend for expansion of abbreviations.
a
Analyses for HIV-related variables are restricted to participants with HIV infection.