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. 1982 Mar;69(3):602–608. doi: 10.1104/pp.69.3.602

Catabolism of Porphobilinogen by Etiolated Barley Leaves 1

Jeffrey X Duggan 1,2, Erna Meller 1, Merrill L Gassman 1
PMCID: PMC426262  PMID: 16662257

Abstract

When [2,4-14C]porphobilinogen (PBG) or [2 (aminomethyl),5-14C]PBG is administered to etiolated barley (Hordeum vulgare L. var. Larker) leaves in darkness, label becomes incorporated into CO2, organic and amino acids, sugars, lipids, and proteins during a 4-hour incubation. Less than 1% of the label, however, is incorporated into porphyrins. The rate of 14CO2 evolution from leaves fed [2,4-14C]PBG is strongly inhibited by anaerobiosis but is unaffected by aminooxyacetic acid, while the rate of 14CO2 evolution from [2(aminomethyl),5-14C]PBG is strongly inhibited by aminooxyacetic acid but is not affected by anaerobiosis.

These results suggest that: (a) exogenous PBG is taken up and metabolized by etiolated barley leaves; (b) PBG is not metabolized exclusively to porphyrins but can be converted to a variety of intermediary metabolites; (c) this metabolism involves reactions which are partially dependent upon O2 and pyridoxal phosphate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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