Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Nov 14;11:96. doi: 10.1186/s12977-014-0096-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Aktar et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

SHAPE and structural analyses of the SL4 domain of the pal II and PBS pal mutants. (A) SHAPE reactivity profile of the wild type and mutant RNAs. Blue boxes indicate pal II, ssPurines, and deletion/substitutions in pal II. Data are an average of at least three independent experiments. (B) Predicted structure of the wild type and mutant SL4 domain in the SHAPE-constrained RNA model by RNAstructure (C) The RNAstructure predicted site of interaction (point of dimerization) between two wild type gRNAs. The central 6 nt of pal II are shown in blue.