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. 1972 Feb;69(2):374–377. doi: 10.1073/pnas.69.2.374

Stimulation of DNA and Protein Synthesis in Fetal-Rat Liver Cells by Serum from Partially Hepatectomized Rats

Dieter Paul *, Hyam Leffert †, Gordon Sato ‡, Robert W Holley *
PMCID: PMC426461  PMID: 4501120

Abstract

Primary cultures of differentiated liver cells from fetal rats respond to serum from partially hepatectomized rats by an increased uptake of [3H]thymidine and [3H]leucine as compared with cultures incubated with normal rat serum. These findings are discussed in relation to the mechanism of induction of DNA synthesis and growth in liver cells during liver regeneration.

Keywords: primary culture, serum factors, proteins, liver regeneration, control mechanism

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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