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. 1972 Jun;69(6):1455–1459. doi: 10.1073/pnas.69.6.1455

Environmental Stimuli in the Progression of BHK/21 Cells Through the Cell Cycle

M Shodell 1
PMCID: PMC426724  PMID: 4504358

Abstract

An L-cell line adapted to grow in protein-free medium is a source of material that stimulates the proliferation of serum-dependent BHK cells under otherwise protein-free conditions. The material produced by the L-cells is resolvable into separate DNA-synthetic and mitotic stimulatory activities. The stimulation of mitosis is dependent upon the presence of one or more heat-labile macromolecules, which can be concentrated by ultrafiltration, and at least one dialyzable component is essential for the initiation of DNA synthesis.

Keywords: L cells, protein-free medium

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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