Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1972 Aug;69(8):2076–2080. doi: 10.1073/pnas.69.8.2076

Serological Detection of a Cell-Surface Antigen Specified by the T (Brachyury) Mutant Gene in the House Mouse

Dorothea Bennett *, Ellen Goldberg *,§, L C Dunn , Edward A Boyse
PMCID: PMC426872  PMID: 4506076

Abstract

A cell-surface component specified by a mutant gene at the T-locus in the mouse has been detected on sperm by serological methods. The gene product thus recognized is not present on other adult cells.

Keywords: autoantigen, embryology, sperm

Full text

PDF
2076

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beatty R. A. The genetics of the mammalian gamete. Biol Rev Camb Philos Soc. 1970 Feb;45(1):73–119. doi: 10.1111/j.1469-185x.1970.tb01076.x. [DOI] [PubMed] [Google Scholar]
  2. DUNN L. C. ABNORMALITIES ASSOCIATED WITH A CHROMOSOME REGION IN THE MOUSE. I. TRANSMISSION AND POPULATION GENETICS OF THE T-REGION. Science. 1964 Apr 17;144(3616):260–263. doi: 10.1126/science.144.3616.260. [DOI] [PubMed] [Google Scholar]
  3. DUNN L. C. BENNETT D, BEASLEY AB: Mutation and recombination in the vicinity of a complex gene. Genetics. 1962 Mar;47:285–303. doi: 10.1093/genetics/47.3.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dunn L C, Suckling J. Studies of the Genetic Variability in Wild Populations of House Mice. I. Analysis of Seven Alleles at Locus T. Genetics. 1956 May;41(3):344–352. doi: 10.1093/genetics/41.3.344. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. GEYER-DUSZYNSKA I. On the structure of the XY bivalent in Mus musculus L. Chromosoma. 1963;13:521–525. doi: 10.1007/BF00321161. [DOI] [PubMed] [Google Scholar]
  6. Goldberg E. H., Aoki T., Boyse E. A., Bennett D. Detection of H-2 antigens on mouse spermatozoa by the cytotoxicity test. Nature. 1970 Nov 7;228(5271):570–572. doi: 10.1038/228570a0. [DOI] [PubMed] [Google Scholar]
  7. Klein J. Cytological identification of the chromosome carrying the IXth linkage group (including H-2) in the house mouse. Proc Natl Acad Sci U S A. 1971 Jul;68(7):1594–1597. doi: 10.1073/pnas.68.7.1594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Monesi V. Synthetic activities during spermatogenesis in the mouse RNA and protein. Exp Cell Res. 1965 Aug;39(1):197–224. doi: 10.1016/0014-4827(65)90023-6. [DOI] [PubMed] [Google Scholar]
  9. Scheid M., Boyse E. A., Carswell E. A., Old L. J. Serologically demonstrable alloantigens of mouse epidermal cells. J Exp Med. 1972 Apr 1;135(4):938–955. doi: 10.1084/jem.135.4.938. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES