Figure 5.

Relatedness tree for Srx sequences. An unrooted phylogenetic tree of 335 Srx sequences is shown. Select organisms or groups of organisms are noted. Sequences were retrieved from the nonredundant protein database by BLAST¹²⁷ on January 31, 2014, with an expect threshold of 100 using the human Srx1 sequence, and additional searches using distantly related Srx sequences did not identify further homologues. Sequences were aligned with MUSCLE,¹³⁸ and evolutionary distances were calculated using PhyML.¹³⁹