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. 1973 Oct;70(10):2863–2865. doi: 10.1073/pnas.70.10.2863

Multiple Common Properties of Human β2-Microglobulin and the Common Portion Fragment Derived from HL-A Antigen Molecules

K Nakamuro 1, N Tanigaki 1, D Pressman 1
PMCID: PMC427126  PMID: 4517941

Abstract

11,000-Dalton common portion fragments derived from HL-A antigen molecules were isolated and found to have a significantly high homology to β2-microglobulin in amino-acid composition. Common portion fragments are also very similar to β2-microglobulin with respect to molecular size, charge, and distribution in tissues. Moreover, both are found in the spent culture media of human cell lines and in human plasma and urine. Thus it appears that β2-microglobulin may well be the same substance as the common portion fragment of HL-A antigen molecules.

Keywords: lymphoid cells, compositional relatedness, histocompatibility

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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