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. 1973 Oct;70(10):2988–2992. doi: 10.1073/pnas.70.10.2988

Surface Antigens Common to Mouse Cleavage Embryos and Primitive Teratocarcinoma Cells in Culture

Karen Artzt *, Philippe Dubois *, Dorothea Bennett *, Hubert Condamine *, Charles Babinet *, François Jacob *
PMCID: PMC427153  PMID: 4355379

Abstract

Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on various types of differentiated teratoma cells derived from the same original tumor. They are negative on all other mouse cells tested, with the exception of male germ cells and cleavage-stage embryos. Thus, teratoma cells possess cell-surface antigens in common with normal cleavage-stage embryos.

Keywords: cytotoxic test, peroxidase-coupled antibody against mouse immunoglobulin, cell differentiation

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Selected References

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