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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1973 Dec;70(12 Pt 1-2):3321–3323. doi: 10.1073/pnas.70.12.3321

Analysis of Gene Diversity in Subdivided Populations

Masatoshi Nei 1
PMCID: PMC427228  PMID: 4519626

Abstract

A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. This method is applicable to any population without regard to the number of alleles per locus, the pattern of evolutionary forces such as mutation, selection, and migration, and the reproductive method of the organism used. Measures of the absolute and relative magnitudes of gene differentiation among subpopulations are also proposed.

Keywords: population structure, genetic variability, heterozygosity, gene differentiation

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Nei M., Roychoudhury A. K. Gene differences between Caucasian, Negro, and Japanese populations. Science. 1972 Aug 4;177(4047):434–436. doi: 10.1126/science.177.4047.434. [DOI] [PubMed] [Google Scholar]
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