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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1973 Dec;70(12 Pt 1-2):3382–3386. doi: 10.1073/pnas.70.12.3382

Microsurgically Fused Human Somatic Cell Hybrids: Analysis and Cloning

Elaine G Diacumakos 1
PMCID: PMC427241  PMID: 4519631

Abstract

Cell fusion by microsurgery permits production of specified bicellular hybrid cells with very high efficiency. Systematic analysis of the fate of bicellular hybrids reveals fundamental properties of cells in accordance with cell type. Bicellular hybrids that do not proliferate survive 1-21 days; those that do proliferate form clones 8-9 days after fusion.

Keywords: hybridization, HeLa, fibroblasts, clone

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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