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. Author manuscript; available in PMC: 2015 Oct 23.
Published in final edited form as: Oncogene. 2014 Jun 23;34(17):2204–2214. doi: 10.1038/onc.2014.168

Figure 6. SERP1 is an important factor in glioblastoma.

Figure 6

(a) SERP1 and (b) NOXA mRNA levels in U87-MG cells grown under the following conditions: Complete Media (C.M.), Serum-Free, Hypoxia (0.5% O2), and Serum Free + Hypoxia (0.5% O2). Cells were transduced with scrambled (Scr) or SERP1 shRNA and subjected to these conditions for 24 hours. * p - value < 0.05; ** p - value < 0.001, (c) SERP1 Open Reading Frame re-expression leads to rescue of cell death in U87-MG expressing miR-124 under hypoxia. (d) SERP1 levels in normal brain and GBM tissues from the TCGA dataset (p - value < 0.0001). (e) Kaplan – Meier survival curve of patients from the REMBRANDT database, stratified by SERP1 expression levels (p - value = 0.006).