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. 1972 Jan;69(1):83–85. doi: 10.1073/pnas.69.1.83

Activation of Epstein-Barr Virus by 5-Bromodeoxyuridine in “Virus-Free” Human Cells

Paul Gerber 1
PMCID: PMC427549  PMID: 4550512

Abstract

Treatment of three human lymphoid cell lines, free of detectable Epstein-Barr virus, with 5-bromodeoxyuridine resulted in activation of virus synthesis in up to 8% of the cells. The induction of infectious virus could be demonstrated by cocultivation experiments with peripheral leukocytes. These studies demonstrated that the entire viral genome may persist in at least a portion of the lymphoid cells.

Keywords: complement-fixing antigen, immunofluorescence, leukocytes

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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