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. 1972 Jan;69(1):86–88. doi: 10.1073/pnas.69.1.86

Growth Inhibition of Sympathetic Cells by Some Adrenergic Blocking Agents

Pietro U Angeletti 1,2, Rita Levi-Montalcini 1,2
PMCID: PMC427550  PMID: 4333047

Abstract

Treatment of newborn mice and rats with the adrenergic blocking agents, guanethidine and bretylium tosylate, results in massive destruction of immature sympathetic nerve cells. A growth inhibition of the same cells is caused by reserpine. Similarities and differences between the effects elicited by these three ganglion blocking agents and a dopamine analog, 6-hydroxydopamine, are discussed.

Keywords: 6-hydroxydopamine, mice and rats, immunosympathectomy, chemical sympathectomy, superior cervical ganglion

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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