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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1972 Jan;69(1):106–108. doi: 10.1073/pnas.69.1.106

Selective Condensation of Aminoacyl Adenylates by Nucleoproteinoid Microparticles

Tadayoshi Nakashima 1,2, Sidney W Fox 1,2
PMCID: PMC427555  PMID: 4500542

Abstract

Microparticles composed of each of four enzymically synthesized homopolynucleotides and the same lysine-rich proteinoid have been found to influence the condensation of the AMP-anhydrides of each of four amino acids. The conditions of preparation of the particles and other variables of the experiments control the types of reaction. When a specified set of conditions was identified empirically, the incorporation favored the amino acids whose present-day codons are related to the homopolynucleotide in the particle.

Keywords: prebiotic, lysine, model system, genetic code

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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