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. 1972 Jan;69(1):162–166. doi: 10.1073/pnas.69.1.162

An Inhibitory Protein of Escherichia coli RNA Polymerase in Bacteriophage T3-Infected Cells

S P Mahadik 1, B Dharmgrongartama 1, P R Srinivasan 1
PMCID: PMC427567  PMID: 4550502

Abstract

A partially purified protein isolated from bacteriophage T3-infected cells of Escherichia coli B markedly inhibits the activity of E. coli RNA polymerase, slightly inhibits the activity of purified T3 polymerase, and does not inhibit the activity of either core polymerase or the ribosome-bound T3 polymerase. The properties of this protein and its mechanism of action have been studied. It appears to antagonize the action of the sigma factor component of RNA polymerase.

Keywords: core polymerase, sigma factor, host polymerase, phage polymerase, initiation

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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