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. 2014 Oct 15;1(10):634–648. doi: 10.18632/oncoscience.87

Figure 1. Cytokine treatment influences ECM protein expression in CAFs.

Figure 1

(A) Western blot showing the effect of treatment of CAFs with ten different growth factors (all at a concentration of 10 ng/ml) on the expression of decorin and α-SMA. Tubulin was used as a loading control. (B) Western blot illustrating the effect of three different concentrations of TGF-β1, bFGF or EGF on the expression of decorin and α-SMA in CAFs. Tubulin was used as a loading control. (C) Table displaying the normalized mRNA expression profile of five SLRP's, two hyalectans, type 1 collagen and α-SMA in CAFs after treatment with bFGF, EGF or TGF-β1, either alone or in combination (10 ng/ml). Red and blue color scales represent 2-, 5- and 10-fold up- and downregulation, respectively. Values are mean ± SD and represent 3 independent experiments.