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. 2014 Oct 15;1(10):634–648. doi: 10.18632/oncoscience.87

Figure 4. Immunohistochemical staining of stromal protein expression in DCIS with sclerotic or myxoid stroma.

Figure 4

Microphotographs displaying HE staining (A-B), and IHC staining for biglycan (C-D), decorin (E-F) and versican (G-H). Panels A-C-E-G display photographs of one DCIS lesion with sclerotic stroma; panels B-D-F-H display one DCIS lesion with myxoid stroma. This figure illustrates that myxoid DCIS present reduced periductal decorin staining and tend to have increased periductal versican and biglycan expression, whereas sclerotic DCIS generally present strong stromal decorin immunoreactivity, and tend to lack stromal versican and biglycan. Original magnification 100x.