Table 3. Top 10 up- and top 10 down-regulated genes in ccRCC versus the normal kidney tissue.
Fold change difference and statistical significance are depicted
| Top 10 up-regulated molecules | Fold change up-regulation | p-value |
| NDUFA4L2 | 53.935 | <0.01 |
| PLIN2 | 27.86 | <0.01 |
| NNMT | 20.86 | <0.01 |
| ENO2 | 19.973 | <0.01 |
| AHNAK2 | 16.622 | <0.01 |
| NETO2 | 15.808 | <0.01 |
| CA9 | 14.483 | <0.01 |
| VWF | 13.061 | <0.01 |
| COL23A1 | 12.752 | <0.01 |
| EHD2 | 12.696 | <0.01 |
| Top 10 down-regulated molecules | Fold change down-regulation | p-value |
| ATP6V0A4 | −19.699 | <0.01 |
| CA10 | −21.452 | <0.01 |
| SLC12A3 | −23.667 | <0.01 |
| CLDN8 | −27.113 | <0.01 |
| SERPINA5 | −35.449 | <0.01 |
| KNG1 | −38.45 | <0.01 |
| KCNJ1 | −50.79 | <0.01 |
| RALYL | −53.576 | <0.01 |
| CALB1 | −103.68 | <0.01 |
| NPHS2 | −159.107 | <0.01 |