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Functions of the proteasome in pol II-mediated transcription. The cartoon shows an idealized mRNA-type gene, with steps shown to be influenced by proteasome function numbered in grey circles 1–5. 1: Controlling the dynamics of activator binding; 2: Controlling co-activator recruitment; 3: Promoting transcriptional elongation; 4: Histone eviction ahead of traveling pol II; 5: Transcription termination.
