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. 2014 Oct 31;5(21):10473–10485. doi: 10.18632/oncotarget.2242

Figure 3. Effect of TP deficiency on NFκB activity.

Figure 3

(A) Yumoto and MCF-7 cells were transfected with control (scrambled) or TP siRNA constructs and NFκB activity was determined using a luciferase reporter construct. (B) KB cells were transfected with control (vector; i.e., KB/CV cells), or wild-type (TP; i.e., KB/TP cells) or mutant (TPmut; i.e., KB/TPmut cells) TP cDNA. TP and IL-8 transcript levels were determined by real-time PCR, and NFκB activity was determined using a luciferase reporter construct.

Data are shown as mean ± SD. *P < 0.01, **P < 0.05.