Fig. 2.

Electron dense and pore-like structures on the surface of vaccinia core. Vaccinia cores were prepared on grids as described in Fig. 1. A) Vaccinia core stained with UA reveal an electro-dense structure in the middle of the particle. B) A globular structure on the middle of the core was enhanced when the grid was subjected to platinum-carbon shadowing. C) The presence of pore-like structures (arrows) was observed after staining cores with NanoW.