Table 2.

Functionality and purity of C1-INH protein concentrates

Content	Berinert	Cetor	Cinryze	Ruconest
Total protein, mean (mg/500 U)	43.2	55.5	48.1	41.2
Batch 1	44.6	55.5	49.3	40.2
Batch 2	41.8	NA	46.8	42.2
Specific activity, mean (U/mg)	11.6	9.0	10.4	12.1
Batch 1	11.2	9.0	10.2	12.4
Batch 2	12.0	NA	10.7	11.8
C1-INH antigen, mean (mg/mL)	13.6	31.3	26.9	55.0
Batch 1	13.1	31.3	25.9	54.3
Batch 2	14.1	NA	27.8	55.8
Ratio antigen to activity,* mean	1.24	1.42	1.22	1.67
Batch 1	1.19	1.42	1.18	1.64
Batch 2	1.28	NA	1.26	1.69

^* C1-INH activity converted from U/mL to mg/mL, 1 U corresponding to 220 μg.