Table 1.

Patient characteristics

Clinical variable	S0313 (n = 46)		S0014 (n = 60)		S8736 (n = 68)
	No.	%	No.	%	No.	%
Age, y
Median	61*		69		66
Range	23-85		26-85		35-85
≥60	26	57	44	73	52	76
Male sex	30	65*	27	45	40	59
White race	43	93	57	95	63	93
Hispanic race	3	7	1	2	2	3
B symptoms	9	20	14	23	14	21
Histology
DLBCL	44	96	56	93	60	88
Burkitt-like	1†	2	3	5	7	10
High-grade B	0	0	1	2	1	1
Mantle cell	1	2	0	0	0	0
LDH > ULN	15	33	13	22	17	25
Stage II	24	52	26	43	32	47
Performance status
0	29	64	42	70	51	75
1	14	31	17	28	15	22
2	2	4	1	2	2	3
Stage-modified IPI risk
1	30	65	42	70	40	59
2	12	26	12	20	21	31
3	3	7	6	10	7	10
4	1	2	0	0	0	0

ULN, upper limit of normal.

^*Statistically significantly different from study S0014, P < .05.

^†The only case of Burkitt-like lymphoma in S0313 was reviewed and confirmed to be Burkitt lymphoma.