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. 2014 Sep 17;40(3):577–589. doi: 10.1038/npp.2014.204

Figure 9.

Figure 9

Locomotor reactivity to novelty, sign-tracking, and anxiety are not associated with altered self-administration or motivation for cocaine. After the assessment of cocaine preference, there was no effect of behavioral traits on the early phase of cocaine self-administration under an FR5 schedule of reinforcement. (a) For 17 days, high (HR, n=8) and low responders (LR, n=10) self-administered cocaine at the same rate, (b) and so did sign- (ST, n=10) and goal-trackers (GT, n=8) and (c) low (LA, n=12) and high (HA, n=12) anxious rats. (d) Motivation for cocaine was measured on the eighteenth day of self-administration by the break point during a progressive ratio session. HR and LR, as well as ST and GT and HA and LA, did not show any significant difference in their break point.