Table 3. Group Differences in Tract Tensor Values.
Tracts |
Fractional anisotropy |
Contrast against controls |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls |
Remitted ADHD |
Persistent ADHD |
Fractional anisotropy |
Radial diffusivity |
Axial diffusivity |
||||||||||
Mean (SD) | Mean (SD) | Mean (SD) |
Persistent vs controls: unadjusted |
Persistent vs controls: adjusted |
Remitted vs controls: unadjusted |
Remitted vs controls: adjusted |
Persistent vs controls: adjusted |
Persistent vs controls: zadjusted |
|||||||
Std β | d | Std β | d | Std β | d | Std β | d | Std β | d | Std β | d | ||||
L inferior fronto-occipital | 0.444 (0.019) | 0.443 (0.018) | 0.431 (0.022) | −0.27a | 0.61 | −0.24 | 0.55 | −0.03 | 0.07 | −0.02 | 0.05 | 0.32a | 0.73 | 0.17 | 0.38 |
R inferior fronto-occipital | 0.451 (0.016) | 0.450 (0.014) | 0.439 (0.02) | −0.30a | 0.68 | −0.28a | 0.63 | −0.01 | 0.02 | −0.01 | 0.02 | 0.29a | 0.67 | 0.05 | 0.11 |
L uncincate | 0.406 (0.024) | 0.403 (0.025) | 0.383 (0.027) | −0.37a | 0.86 | −0.32a | 0.73 | −0.05 | 0.11 | −0.05 | 0.11 | 0.31a | 0.71 | 0.09 | 0.21 |
R uncincate | 0.400 (0.021) | 0.394 (0.016) | 0.384 (0.024) | −0.31a | 0.72 | −0.28a | 0.54 | −0.13 | 0.26 | −0.13 | 0.27 | 0.29a | 0.66 | 0.13 | 0.29 |
L corticospinal | 0.421 (0.016) | 0.418 (0.013) | 0.411 (0.016) | −0.26a | 0.60 | −0.23 | 0.52 | −0.09 | 0.18 | −0.09 | 0.19 | 0.04 | 0.09 | 0.001 | 0.00 |
R corticospinal | 0.437 (0.016) | 0.433 (0.014) | 0.429 (0.017) | −0.21 | 0.22 | −0.17 | 0.38 | −0.12 | 0.24 | −0.11 | 0.24 | −0.01 | 0.01 | −0.07 | 0.14 |
L superior longitudinal | 0.438 (0.016) | 0.438 (0.017) | 0.429 (0.02) | −0.21 | 0.46 | −0.17 | 0.38 | −0.004 | 0.01 | 0.01 | 0.01 | 0.29a | 0.65 | 0.20 | 0.44 |
R superior longitudinal | 0.493 (0.022) | 0.494 (0.022) | 0.478 (0.024) | −0.26 | 0.58 | −0.24 | 0.54 | 0.03 | 0.01 | 0.03 | 0.06 | 0.30a | 0.69 | 0.15 | 0.34 |
L inferior longitudinal | 0.322 (0.031) | 0.328 (0.033) | 0.328 (0.034) | 0.08 | 0.17 | 0.09 | 0.21 | 0.08 | 0.17 | 0.09 | 0.18 | 0.08 | 0.17 | 0.29a | 0.66 |
R inferior longitudinal | 0.313 (0.031) | 0.311 (0.03) | 0.315 (0.033) | 0.02 | 0.05 | 0.06 | 0.13 | −0.03 | 0.06 | −0.02 | 0.04 | 0.12 | 0.27 | 0.32a | 0.76 |
Corpus callosum | 0.455 (0.015) | 0.459 (0.014) | 0.455 (0.017) | −0.10 | 0.22 | −0.08 | 0.17 | 0.02 | 0.05 | 0.02 | 0.04 | 0.08 | 0.18 | 0.14 | 0.31 |
Columns 2–4 show the mean (SD) of the fractional anisotropy for each tract. The next columns give the standardized β coefficients for the planned contrasts of the persistent and remitted ADHD groups against the never-affected comparison, ‘control' group (unadjusted and adjusted) with the associated effect size (d). The final columns show radial and axial diffusivities for the persistent against the comparison group; there were no significant differences between the remitted and comparison group.
Survives Bonferroni adjustment for multiple comparisons.
Results in bold indicate those surviving Bonferroni adjustment for multiple comparisons.