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. 1974 May;5(5):538–540. doi: 10.1128/aac.5.5.538

Mutant of Staphylococcus aureus with Lincomycin- and Carbomycin-Inducible Resistance to Erythromycin

Teruo Tanaka 1, Bernard Weisblum 1
PMCID: PMC429007  PMID: 4462467

Abstract

A mutant of Staphylococcus aureus was isolated in which lincomycin and carbomycin (but not erythromycin) induced resistance to erythromycin. This pattern displayed a reversal of the usual specificity of induction seen in the erythromycin-inducible parent strain from which the mutant was selected.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Lai C. J., Dahlberg J. E., Weisblum B. Structure of an inducibly methylatable nucleotide sequence in 23S ribosomal ribonucleic acid from erythromycin-resistant Staphylococcus aureus. Biochemistry. 1973 Jan 30;12(3):457–460. doi: 10.1021/bi00727a015. [DOI] [PubMed] [Google Scholar]
  2. Lai C. J., Weisblum B. Altered methylation of ribosomal RNA in an erythromycin-resistant strain of Staphylococcus aureus. Proc Natl Acad Sci U S A. 1971 Apr;68(4):856–860. doi: 10.1073/pnas.68.4.856. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Lai C. J., Weisblum B., Fahnestock S. R., Nomura M. Alteration of 23 S ribosomal RNA and erythromycin-induced resistance to lincomycin and spiramycin in Staphylococcus aureus. J Mol Biol. 1973 Feb 15;74(1):67–72. doi: 10.1016/0022-2836(73)90355-0. [DOI] [PubMed] [Google Scholar]
  4. Saito T., Shimizu M., Mitsuhashi S. The problems of drug-resistant pathogenic bacteria. Macrolide resistance in staphylococci. Ann N Y Acad Sci. 1971 Jun 11;182:267–278. doi: 10.1111/j.1749-6632.1971.tb30663.x. [DOI] [PubMed] [Google Scholar]
  5. Weisblum B., Demohn V. Erythromycin-inducible resistance in Staphylococcus aureus: survey of antibiotic classes involved. J Bacteriol. 1969 May;98(2):447–452. doi: 10.1128/jb.98.2.447-452.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Weisblum B., Siddhikol C., Lai C. J., Demohn V. Erythromycin-inducible resistance in Staphylococcus aureus: requirements for induction. J Bacteriol. 1971 Jun;106(3):835–847. doi: 10.1128/jb.106.3.835-847.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]

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