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. 1975 Jan;7(1):113–114. doi: 10.1128/aac.7.1.113

Comparison of Broth and Human Serum as the Diluent in the Serum Bactericidal Test

F D Pien 1, R D Williams 1, K L Vosti 1
PMCID: PMC429083  PMID: 1137355

Abstract

The use of serum rather than broth as the diluent in the serum bactericidal test results in a significant decrease in the test level among patients receiving highly protein-bound semisynthetic penicillins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Kunin C. M. Clinical pharmacology of the new penicillins. 1. The importance of serum protein binding in determining antimicrobial activity and concentration in serum. Clin Pharmacol Ther. 1966 Mar-Apr;7(2):166–179. doi: 10.1002/cpt196672166. [DOI] [PubMed] [Google Scholar]
  2. Pien F. D., Vosti K. L. Variation in performance of the serum bactericidal test. Antimicrob Agents Chemother. 1974 Sep;6(3):330–333. doi: 10.1128/aac.6.3.330. [DOI] [PMC free article] [PubMed] [Google Scholar]

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