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. 1975 Feb;7(2):164–167. doi: 10.1128/aac.7.2.164

Susceptibility of Various Serogroups of Streptococci to Clindamycin and Lincomycin

Adolf W Karchmer *, Robert C Moellering Jr *, Barbara K Watson *
PMCID: PMC429097  PMID: 1137367

Abstract

The minimal inhibitory concentration of lincomycin and clindamycin for a large number of strains from multiple serogroups of streptococci was determined. The median minimal inhibitory concentration for streptococci from groups A, B, C, F, G, H, L, and M and nongroupable organisms ranged from 0.02 to 0.39 μg of lincomycin per ml and from ≤0.01 to 0.09 μg of clindamycin per ml. Among the group D strains, Streptococcus faecium and Streptococcus faecalis were resistant to lincomycin and clindamycin, whereas Streptococcus bovis and four American strains of Streptococcus durans resembled nongroup D isolates in their susceptibility to these agents. Occasional strains of nongroup D streptococci were highly resistant to lincomycin and clindamycin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DEIBEL R. H. THE GROUP D STREPTOCOCCI. Bacteriol Rev. 1964 Sep;28:330–366. doi: 10.1128/br.28.3.330-366.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dixon J. M., Lipinski A. E. Resistance of group A beta-hemolytic streptococci to lincomycin and erythromycin. Antimicrob Agents Chemother. 1972 Apr;1(4):333–339. doi: 10.1128/aac.1.4.333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Facklam R. R. Comparison of several laboratory media for presumptive identification of enterococci and group D streptococci. Appl Microbiol. 1973 Aug;26(2):138–145. doi: 10.1128/am.26.2.138-145.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fass R. J., Saslaw S. Clindamycin: clinical and laboratory evaluation of parenteral therapy. Am J Med Sci. 1972 May;263(5):368–382. [PubMed] [Google Scholar]
  5. KAPLAN K., CHEW W. H., WEINSTEIN L. MICROBIOLOGICAL, PHARMACOLOGICAL AND CLINICAL STUDIES OF LINCOMYCIN. Am J Med Sci. 1965 Aug;250:137–146. doi: 10.1097/00000441-196508000-00003. [DOI] [PubMed] [Google Scholar]
  6. McCall C. E., Steigbigel N. H., Finland M. Lincomycin: activity in vitro and absorption and excretion in normal young men. Am J Med Sci. 1967 Aug;254(2):144–155. [PubMed] [Google Scholar]
  7. McGehee R. F., Jr, Smith C. B., Wilcox C., Finland M. Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. Am J Med Sci. 1968 Nov;256(5):279–292. doi: 10.1097/00000441-196811000-00002. [DOI] [PubMed] [Google Scholar]
  8. Moellering R. C., Jr, Watson B. K., Kunz L. J. Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. Am J Med. 1974 Aug;57(2):239–250. doi: 10.1016/0002-9343(74)90448-3. [DOI] [PubMed] [Google Scholar]
  9. RANTZ L. A., RANDALL E. Use of autoclaved extracts of hemolytic streptococci for serological grouping. Stanford Med Bull. 1955 May;13(2):290–291. [PubMed] [Google Scholar]
  10. Toala P., McDonald A., Wilcox C., Finland M. Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. Am J Med Sci. 1969 Dec;258(6):416–430. doi: 10.1097/00000441-196912000-00006. [DOI] [PubMed] [Google Scholar]

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