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. 1975 Mar;7(3):281–284. doi: 10.1128/aac.7.3.281

Activity of Pure Streptovaricins and Fractionated Streptovaricin Complex Against Friend Virus

Julius S Horoszewicz *, Kenneth L Rinehart Jr †, Susan S Leong †, William A Carter †
PMCID: PMC429124  PMID: 237470

Abstract

Chromatographic fractionation of streptovaricin complex yields two stable components enriched (4- to 16-fold) in activity directed against the polycythemic strain of Friend virus; both components apparently contain no streptovaricins. When compared with their unfractionated parent streptovaricin complex, eight individual intact streptovaricins (A through G and J) show at least a 30-fold reduction in antiviral activity. These results further support the conclusion that the diversified biological properties of streptovaricin complex probably reside in different molecular structures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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