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Exogenous Zn2+ causes sensor-dependent changes in fluorescence for intracellular Zn2+ sensors. (A) %-Increase in FluoZin fluorescence (relative to vehicle-treatment) in PC3 and C4-2 cells following treatment with ZnPy (“*” indicates p < 0.05 for both cell lines). B – D are confocal images of C4-2 cells: B – no treatment; C – 6 μM ZnPy with Zinquin detection; D – 6 μM ZnPy with FluoZin detection.
