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. 1975 Nov;8(5):538–543. doi: 10.1128/aac.8.5.538

Human Therapeutic and Agricultural Uses of Antibacterial Drugs and Resistance of the Enteric Flora of Humans

D Siegel a,1, W G Huber a,1, S Drysdale a
PMCID: PMC429416  PMID: 1108775

Abstract

Fecal samples were collected from five groups of people differing in the manner of their exposure to antibacterial drugs. The groups included: (i) people working on farms who were continuously in contact with the predominantly resistant florae of farm animals receiving rations containing antibacterial drugs, (ii) people residing on the same farms with no direct exposure to the farm animals, (iii) people treated with antibacterial drugs, (iv) untreated people residing with treated individuals, and (v) untreated people with no exposure to farm animals or treated individuals. The samples were examined by quantitative plating for proportions of antibiotic-resistant, gram-negative enteric organisms. Individual isolates were also examined for their susceptibility to 11 different antibacterial drugs. The results indicate that enteric florae unexposed directly to the selective effects of antibacterial drugs may be affected by contact with predominantly resistant florae directly exposed to antibacterial drugs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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